Gut Microbiome in Chronic Pancreatitis
- As a Master’s student ready to begin my thesis I was motivated to continue working on a project that would utilize a cutting-edge technology to study the gut microbiome which I was very excited about.
- This excitement being contagious, I managed to convince my thesis supervisor to invest in a Nanopore sequencer for the lab.
- I used this opportunity to optimize protocls and setup the Nanopore sequencer in the lab and developed my bioinformatic skills starting with setting up a Linux workstation for the lab and implementing a bioinformatic pipeline for metagenomics analysis.
- I developed an end-to-end sampling and sequencing pipeline for metagenomics analysis of fecal samples using Nanopore sequencing in collaboration with a nearby hospital.
- In collaboration with a gastroenterologist we analyzed the human gut microbiome in chronic pancreatitis patients and compared them with healthy samples to identify disease-related changes in the gut microbiome.